The game was received positively by critics, garnering acclaim for its style, humour and its faithfulness to Theme Hospital's aesthetics, but criticised for its repetitiveness and room design. Within weeks of release, Two Point Hospital was the second most downloaded game in the sales charts for Europe, Middle East, Africa, and Australia.

The game was designed and developed by some of the creators of Theme Hospital, including Mark Webley and Gary Carr. Since visiting real hospitals is often unpleasant, the emphasis on humour to lighten the mood was deemed important by the developers. A spiritual successor to Bullfrog Productions' 1997 game Theme Hospital, players are tasked with constructing and operating an empire of hospitals in the fictional Two Point County, with the goal of curing patients of fictitious, comical ailments. A version for Amazon Luna was also made available in November 2020. Console versions for the Nintendo Switch, PlayStation 4, and Xbox One were released in February 2020. Two Point Hospital is a 2018 business simulation game developed by Two Point Studios and published by Sega for Linux, macOS, and Windows.

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